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This should increase conversion of cystathionine to homocysteine 32 which may ultimately provide SAM, via the methyl/methionine cycle 51 for EGT biosynthesis (Fig

This may well be relevant for other neurodegenerative diseases

Additionally, dopamine modification of DNA through dopaminylation at histones has been identified in animal models of cocaine exposure, identifying a novel method of gene expression regulation mediated by dopamine (Lepack et al., 2020)