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Sun W, Liu R, Gao X, Lin Z, Tang H, Cui H, et al

1 Benefits of glutathione to eye health 4 The neurodegenerative eye disease glaucoma, a leading cause of irreversible blindness worldwide is characterised by progressive damage or degeneration of the optic nerve from oxidative stress, and lower levels of glutathione have been observed in those with the condition, compared to controls

Overall, GPX4 plays a significant role in suppressing ferroptosis by reducing lipid peroxidation through GSH consumption, thereby alleviating pain, which suggests that interventions targeting GPX4 may hold promise as novel therapeutic strategies for pain management [51, 58]

10.1016/j.mce.2018.10.019