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This longevity of research interest is itself informative: compounds that fail to replicate across independent laboratories typically disappear from the literature within a decade

There is a lapse rate, meaning a 2 degree Celsius drop in temperature per every 1,000 feet increase in altitude

Hair burning and liming in tanneries is a source of pollution by arsenic, lead, zinc, manganese and iron

Next, we disrupted the nuclear localization sequence in TDP-43 (TDP-43 NLSmut ) to mislocalize TDP-43 to the cytoplasm and found that in response to sodium arsenite, TDP-43 NLSmut blocks SUMOylation indicating that nuclear localization is essential for TDP-43 SUMOylation (Fig