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In addition, SA has been shown to stabilize auxin repressor protein AUX/IAA by inhibiting the expression of TIR1/AFB transport inhibitor resistant1)/(auxin signaling F-BOX), thereby inhibiting auxin response and enhancing plant resistance [81]

This effect is accompanied by substantial depletion of glutathione (GSH) [54]

A specific protease cleavage site, such as the one recognized by HRV 3C protease (Leu-Glu-Val-Leu-Phe-GlnGly-Pro), can be engineered between the GST tag and the target protein

However, in livers of Gpx4 fl/fl AlbCreERT2 Tg/+ animals fed CDAHFD, loss of hepatocyte Gpx4 caused no alterations (other than diet-induced MASH) (Fig