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Also enriched were transcripts playing roles in metabolism, including Ilp2-RA , the only isoform of the gene encoding the Drosophila Insulin-like peptide 2, knock-out of which has been shown to extend lifespan [ 31 ]

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Furthermore, their anti-inflammatory and antioxidant properties were shown by their ability to inhibit the MAPKNFB signaling pathway and activate the Nrf2HO-1 pathway, respectively