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Goral V

Biochem Soc Trans

Scott et al

Evidence supports: Low glycemic index/glycemic load eating pattern: Reduces insulin and IGF-1 signalling, and supports healthy weight, which reduces aromatase-driven estrogen production Increased intake of cruciferous vegetables: Provide DIM (diindolylmethane) precursors that support Phase I/II estrogen metabolism Omega-3 fatty acids: EPA/DHA reduce pro-inflammatory prostaglandin production (PGE2), relevant to heavy bleeding Reduced alcohol: Alcohol raises estradiol levels and impairs hepatic estrogen clearance Food sensitivity identification: Chronic dietary-driven intestinal inflammation can contribute to systemic inflammatory load