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No kdr mutation has been detected so far in this species 12 despite the widespread report of insecticide resistance in An

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On the other hand, iron-triggered lipid peroxidation activates matrix metalloproteinase-9 (MMP-9), which degrades key tight junction proteins such as ZO-1 and occludin, thereby disrupting endothelial barrier structure and increasing vascular permeability (Kim et al., 2022)