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Comprehensive analysis of gut microbial community structural characteristics, metabolite characteristic profiles, and clinical phenotype information promises discovery of critical pathogenic pathways and potential intervention targets (163) Targeted metabolic pathway intervention trials: randomized controlled clinical studies directed at specific metabolic pathways should be designed

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Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults