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doi: 10.1128/aac.02284-19 120 FernandesK

Critically, the study also demonstrated that glutaminase inhibition may preferentially radiosensitize KEAP1 -mutant cells through the depletion of glutathione, a key endogenous antioxidant

It was demonstrated in the ferroptosis model of SH-SY5Y cells that the increase of GPX4 expression by dauricine suppressed ferroptosis in SH-SY5Y cells caused by RSL3 and enhanced cell survival ( in vivo and in vitro