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Five studies of BPC-157 reviewed by the agency "were of short duration, had small sample sizes and evaluated doses that were likely exploratory in nature," the staffers said

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The glycolytic enzymes characterized by significantly downregulated transcription upon infection were hexokinase 2 ( HK2 ), glucose6phosphate isomerase ( GPI ), phosphofructokinase liver type ( PFKL ), aldolase fructosebisphosphate C ( ALDOC ), triosephosphate isomerase 1 ( TPI1 ), and enolase 2 ( ENO2 ), thus suggesting a broad downregulation of the glycolytic pathway (Fig 1B)

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