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Activation of p53 repressed the transcription of VKORC1L1 by binding to the p53-binding sequence in the promoter [116]

Proteinprotein interactions are essential, with TXNIP facilitating NLRP3 activation under oxidative stress, with NEK7 being critical for inflammasome assembly via interaction with the LRR domain and with HSP90/SGT1 stabilizing the inactive form [41]

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Othman, H., Hassan, R., Faizullah, A