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These conversions result in the production of glucuronide and sulfate, curcumin compounds that render curcumin more bulky (which further limits curcumin uptake across the gut wall, meaning that a significant proportion of curcumin is excreted unabsorbed in the faeces) and water-soluble (allowing any absorbed curcumin to be easily excreted by the kidneys)

Commenters noted that these burdens might negatively impact participation in prepaid shared savings

J Cyst Fibros 12:352362

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