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This network would be (i) derived from longitudinal pharmacotherapy, ECT, and MST experiments through therapeutic network mapping, (ii) validated by independent longitudinal datasets, (iii) annotated by depression-related genetic, molecular, and cognition networks, and (iv) tested for generalizability to DBS and rTMS

Oxidation of the polyunsaturated butadienyl portion of the dye results in a shift of the fluorescence emission peak from approximately 590 to approximately 510 nm