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(111) studied Huntingtons gene-mutant mice and found that EODF slowed disease progression, increased survival rates, improved motor performance, reduced brain atrophy, and decreased huntingtin aggregate formation and caspase activation, normalized glucose regulation, and restored BDNF and chaperone protein levels in the cortex and striatum compared to the AL group

Neuroinflammation in AD is largely driven by activated microglia and astrocytes, which respond to A plaques by releasing pro-inflammatory cytokines

Zhang W, Konopleva M, Y-X S, Harris D, Small D, Ling X, Estrov Z, Cortes J, Andreeff M

Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB (2007) Bioavailability of Curcumin: problems and promises