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Importantly, ROS can further augment the overall antimicrobial response of PMNs by activating the release of granules, inducing the generation of neutrophil extracellular traps (NETs), and stimulating the production of the pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF) and macrophage inflammatory protein 2 (MIP-2) (Brinkmann et al., 2011

This amount accounts for a smaller body size and different metabolism rates

Rapid weight loss outpaces the skins ability to remodel, and substrate availability tightens