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In recent years, it has gained popularity as a treatment for depression and other mental health conditions, administered through intravenous infusion

AATD Alpha-1-antitrypsin deficiency BiP Immunoglobulin heavy chain-binding protein CFTR Cystic fibrosis transmembrane conductance regulator CXCR4 C-X-C chemokine receptor type 4 ER Endoplasmic reticulum ERAD ER associated degradation Ero1 Endoplasmic reticulum oxidoreductin 1 Gpx Glutathione peroxidase GR Glutathione reductase Grx Glutaredoxin GSH/GSSG Reduced/oxidized glutathione HMGB1 High mobility group protein B1 KEAP1 Kelch-like ECH-associated protein 1 MD2 Lymphocyte antigen 96 Nrf2 Nuclear factor erythroid 2-related factor 2 PDI Protein disulfide isomerase Prx Peroxiredoxin PTEN Phosphatase and tensin homolog QSOX Quiescin sulfhydryl oxidase RAGE/ARGE Advanced glycosylation end product-specific receptor ROS Reactive oxygen species SOD1 Superoxide Dismutase 1 TLR4 Toll-like receptor 4 TNF Tumor necrosis factor TNFR TNF receptors Trx Thioredoxin TrxR Thioredoxin reductase VkOR Vitamin K epoxide reductase

coli AGE assay ELISA was used to detect carboxymethyl-lysine levels as in Pepper et al 26 with 100 l of supersensitive, 3,3,5,5-tetramethylbenzidine (TMB) (Sigma) used as the color reagent and read at 630 nm on a BioTek ELx808 absorbance reader

Dosage must be calculated based on body weight, and injections should be given by trained healthcare professionals