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Hassler et al., Further research is needed to understand underlying mechanisms of NP that allow to design individual and rational treatment strategies

Gutsche, N

Similarly, a histone methyltransferase inhibitor (BRD4770) was used as a novel inhibitor of ferroptosis in smooth muscle cells (SMCs) induced by cystine deprivation, imidazolone erastin or RSL3.The activation of NF-B signaling induced by these three stimuli was reversed by BRD4770, protecting SMCs from ferroptosis (195)