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For instance, genes like KCNK3 and GAS5 demonstrate dual functionality in both blood pressure regulation and tumor suppression, highlighting epigenetic plasticity as a mediator of comorbid disease risk [69, 70, 274,275,276]

Specific knockdown of the NDUFS4 gene reveals important roles of ferroptosis in UVB-induced photoaging

Mechanisms of hyperglycemia-induced damage There are nearly 2000 publications supporting five major mechanisms by which hyperglycemia causes diabetic complications: 1 Increased flux of glucose and other sugars through the polyol pathway