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Furthermore, changes in body composition may be due to changes in energy intake as a result of decreasing circulating concentrations appetite-related hormones such as leptin [73, 89]

gC and gB can also bind to C-type lectin dendritic cell-specific ICAM3-grabbing nonintegrin (DC-SIGN), facilitating dendritic cell infection

Each of these points reflects findings from the experimental literature rather than approved indications

For example, drinking coffee would have the same effect as the synthetic caffeine in most of these pre-workout products, so we would not necessarily need a pre-workout supplement for this effect