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Next, we will elucidate how diabetes and its associated metabolic and microbiota dysregulation disrupt the equilibrium of innate and adaptive immune cells in the lung, leading to uncontrolled inflammation and tissue damage (Figure 5)

doi: 10.1038/jid.2012.261 198 FriedmannPSWrenFEMatthewsJN

According to the American Diabetes Association (ADA), if the patients glycemic status remains uncontrolled, insulin remains the preferred medication for treating hyperglycemia and achieving an adequate glycemic status

This could be due to a PPAR-mediated inhibition of apoCIII, promoting the clearance of apoB100-associated lipoproteins [116]