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Abbreviations AA: Ascorbate APX: Ascorbate peroxidase CAT: Catalase DHA: Dehydroascorbate DHAR: Dehydroascorbate reductase GR: Glutathione reductase GSH: Reduced glutathione GSSG: Oxidized glutathione MDHAR: Monodehydroascorbate reductase O 2 : Superoxide anion radical OH: Hydroxyl radical ROS: Reactive oxygen species SOD: Superoxide dismutase TFs: Transcription factors References Abdel-Ghany SE, Mller-Moul P, Niyogi KK, Pilon M, Shikanai T (2005) Two P-type ATPases are required for copper delivery in Arabidopsis thaliana chloroplasts

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents

GSH, the most abundant antioxidant in the heart, plays a fundamental role in normalizing a redox homeostatic mechanism that was shifted toward oxidative or reductive stress