glutathione peroxidase 1 gene Trait: Oxidative Stress Risk (GPx-1)

J Neurosci 34:717725 Li S, Wu Q, Sun Q, Coffin S, Gui W, Zhu G (2019) Parental exposure to tebuconazole causes thyroid endocrine disruption in zebrafish and developmental toxicity in offspring

186 Most importantly, DNA damage-induced activation of ataxia-telangiectasia mutated- and Rad3-related protein (ATR) promotes Ser132 and Ser368 phosphorylation of USP20, enhancing its stability and conferring oxaliplatin- and ferroptosis-resistance in HCC cells

Collectively, these results indicate a probable link between IBD and ferroptosis, such as disruption of IECs and damage to the intestinal mucosal barrier, which ultimately results in the development of IBD

In this section, we review the therapeutic potential of targeting macrophage polarization in ovarian cancer ( Table 1 ) ( Figure 6 ): Table 1 Treatment targeting macrophage polarization in ovarian cancer