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Lands et al., 1999

Glia 65 , 12271250 (2017)

Sulforaphane Mitigates Muscle Fibrosis in Mdx Mice via Nrf2-Mediated Inhibition of TGF-/Smad Signaling

During programmed cell death, cleaved caspase-3 cuts PARP into distinct fragments, effectively halting its repair functions and locking the cell into an irreversible death program