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Liu S, Hu W, Wang Z, Chen T

10.3390/ijms23094551 13 AsmamawM.ZawdieB

In the same vein, the Randomized European Celecoxib Trial, a phase 3, randomized, double-blind study (NCT02429427), did not show any evidence of DFS benefit in breast cancer patients [293]

This copper-mediated Fenton-like chemistry can inflict extensive cellular damage, including DNA strand breaks, protein oxidation and denaturation, lipid peroxidation, and ultimately cell death (Adlard and Bush 2006