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A deficiency in either of these vitamins can cause a wide range of problems, including: extreme tiredness a lack of energy pins and needles (paraesthesia) a sore and red tongue mouth ulcers muscle weakness disturbed vision psychological problems, which may include depression and problems with memory, understanding and judgement Some of these problems can also happen if you have a deficiency in vitamin B12 or folate but do not have anaemia

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The catch is that a compounded drug product qualifies for these exemptions only if the bulk drug substance used to make it meets one of three criteria: (1) it complies with a USP or National Formulary monograph

10.1515/zpch-1929-0403 345 KumarR.MoureC