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doi: 10.1016/j.freeradbiomed.2011.03.018

Hseu YC, Vudhya Gowrisankar Y, Chen XZ, Yang YC, Yang HL

KalghatgiSSpinaCSCostelloJCLiesaMMorones-RamirezJRSlomovicSet al

The GI microbiota tends to deconjugate and reduce hepatic xenobiotic metabolites, resulting in the formation of non-polar molecules of lower molecular weight, which are readily reabsorbed