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Irreversible thiol oxidation in carbonic anhydrase III: protection by S-glutathiolation and detection in aging rats

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The value of GSH and nutritional strategies like amino acids, vitamins, minerals, phytochemicals, sulforaphane to enhance cellular Nrf2, and other supplements used to restore GSH levels (Minich and Brown, 2019

Consistent results showed that GSH synthesis rate is significantly increased in cells overexpressing WT GCLC or its K-R mutants (K38R, K126R, K326R, 3KR) (Fig