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Spine, 33 , 14031409

During cardiac stress, ischemic injury, and metabolic syndrome in the cardiovascular system, necrotic cells release DAMPs, which are recognized by pattern recognition receptors on innate immune cells, triggering strong inflammatory responses

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Discussion This is the first systematic review and meta-analysis in which the efficacy, acceptability, and safety of mitochondrial modulators (eicosapentaenoic acid, folic acid, inositol, lithium, N -acetylcysteine, and silymarin) were compared with those of conventional treatment for OCD and OCD-related disorders