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Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial

An overflow of glutamate (the main endogenous excitatory amino in brain, at concentration of 515 mmol glutamate per kg body weight, higher than of any other neurotransmitter) is implicated in major psychiatric illnesses [1, 24,25,26]

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This alkaloid also causes the secretion of another enterohormone, cholecystokinin, which stimulates bile production and gallbladder motility and relaxes the sphincter of Oddi, allowing bile and pancreatic juice to drain into the duodenum