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Nonetheless, certain aspects of ASD symptomatology such as inflammation and oxidative stress seem to be shared by many ASD mouse models [19]

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Forsythoside A also activates the Nrf2/GPX4 axis to inhibit iron deposition-mediated neuroinflammation and lipid peroxidation, preventing the IKK/IB/NF-B signaling, reducing pro-inflammatory cytokine secretion to improve memory and cognitive function in Alzheimers-like pathology [82]