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The sex-specific phenotype in Se metabolism is rather well-described the reader is referred to the review by Seale et al

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As per the etiology of depression, several factors are highlighted in current reviews, such as genetic factors, hormones, HPA axis, and environmental factors [113]

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In addition to DAMPs, pathogen-associated molecular patterns such as viral RNA or the bacterial cell wall component lipopolysaccharide (LPS) may also maintain neuroinflammation

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5A) revealed that single biomarkers (e.g., serum CRP and triglycerides) have limited discriminative power, whereas integrated domainsphospholipid remodeling, lipotoxicity, and mitochondrial dysfunctiontogether with antioxidant status, acute phase response, and reduced ApoA1are the principal contributors

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