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PubMed PMID: 20171854

Topical chemotherapy Dermal drug delivery represents a broad term used to address the administration of dosage forms via transdermal (across) or topical (into) the skin [239]

Activation of caspase-4 subsequently activates GSDMD, and the Damage-Associated Molecular Pattern (DAMPs) released can activate the inflammasome (Kayagaki et al., 2015