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doi: 10.1128/JVI.65.11.5757-5764.1991 101 KanaiRWakimotoHMartuzaRLRabkinSD

The ratio of -KG produced by glutamine metabolism to succinic acid affects the activation of M2 macrophages

Results ASP inhibited cell proliferation and tumor growth in EC cells and the Lkb1 fl/fl p53 fl/fl mouse model of EC fl/fl fl/fl The anti-proliferative effects of different concentrations of ASP on the ECC-1, HEC-1A, KLE, and Ishikawa were evaluated using MTT assay