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11 Discussion on nano delivery or formulation strategies The therapeutic use of apigenin and ellagic acid is limited by poor oral bioavailability due to low solubility, rapid metabolism, and restricted permeability (82)

This article also reviewed network pharmacology analyses published previously to identify and explore the potential molecular targets of Rg1 in PD treatment, while evaluating strategies such as drug delivery technologies, optimizing administration routes, and combination therapies

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