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This article examines whether berberine changes stool colour, explores the mechanisms behind such changes, and provides guidance on distinguishing benign effects from symptoms requiring medical attention

Moreover, 5 mg/kg 3-bromopyruvate (glycolysis inhibitor) in a mouse with arthritis induced by K/BxN mouse serum reduces clinical score, proinflammatory cytokines in the joint, inflammatory cell infiltration, joint destruction, and cartilage damage 27 , which has made it possible to consider glycolysis pathway inhibition as a potential pharmacological target for RA 29

As shown in Figures 3CE, the activities of cleaved caspase 3, 8, and 9 were increased in a dose-dependent manner by treatment with increasing concentrations of ASP for 12 h in both cell lines

Mitochondrial peptides in aging & metabolic disease