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3 To prevent excessive oxidative stress and maintain favorable redox homeostasis, tumor cells have evolved a complex antioxidant defense system that strategically adjusts multiple antioxidant enzymes such as catalase, glutathione reductase, and antioxidant molecules

Although the consequences of GSH depletion have been described previously, questions remain regarding the molecular mechanisms

P values for one-tailed T.test no Ab vs 96 hrs AIIB2 are 2.7 10^-4 for ANPEP, 5.39 10^-7 for CYP2c9, 2.8 10^-5 for CYP2C19, and 1.92 10^-4 for TFF3