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Third, establishing sophisticated preclinical models, such as patient-derived organoids and humanized tumor xenografts, to accelerate the clinical translation of multimodal combination therapies targeting this axis

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The pharmacist plays a critical role in advocating treatment regimens that address administration needs while keeping patient care a priority

However, we used leave-one-out sensitivity analysis under a conservative random-effects model to assess the possibility of some bias such as unclear double-randomization or large unbalanced dropout