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10.1038/nrn3406 75 LevinJ.SchmidtF.BoehmC.PrixC.BtzelK.RyazanovS.et al

Another adaptation to exercise involves the enhancement of mitochondrial biogenesis via upregulated peroxisome proliferator-activated receptor- coactivator-1 (PGC-1) gene expression (Steinbacher and Eckl, 2015)

Exogenous antioxidants at pharmacological doses could be useful for chemotherapeutic purposes, while at dietary doses, they might be useful in chemoprevention