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Description

Nephron loss, nephron hypertrophy, impaired glomerular filtration, and fibrosis are summarized as primary pathophysiological characteristics of CKD (Romagnani et al., 2017)

Auchere, F

22 (1), 2126 (2019) M

Its weighing whether the substance can be consistently characterized, whether there are safety concerns (including impurities and immunogenicity), and whether the proposed uses have any credible evidence behind them