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Initial stratification should integrate pre-treatment tumor genomics/epigenetics with host parameters to construct predictive models, and then longitudinal monitoring of tumor evolution under therapeutic pressure enables adaptive treatment adjustments

Of concern, reduced 5-HIAA levels in the CSF and SERT density have also been reported in human ecstasy users, what has been interpreted to reflect the loss of serotonergic fibers and terminals

Kang KA, Piao MJ, Hyun YJ, Zhen AX, Cho SJ, Ahn MJ et al (2019) Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

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