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Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions

Liu XC, Hubbard JA, Fabes RA, Adams JA, et al: Sleep Disturbances and Correlates of Children with Autism Spectrum Disorders

Both intra- and intersubunit interactions are considered to be key determinants of the allosteric response, which involves switching of the PK tetramer from the low-affinity T state to the high-affinity R state

47 In an open-label substudy of patients with type 2 diabetes and MASH (n = 502), tirzepatide resulted in a significant reduction in liver fat compared with insulin degludec after 52 weeks