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Description

Careful review prevents costly preparation errors during mixing steps

Additional glutamine residues can confer toxicity through various mechanisms, including irregular protein folding and degradation pathways, altered subcellular localization, and aberrant interactions with other cellular proteins [141]

Among the chemically synthesized AOPs, SS-31 (d-Arg-Dmt-Lys-Phe-NH2) exerts antioxidant effects primarily attributed to the Dmt residue, enabling it to selectively target mitochondria and localize in the inner mitochondrial membrane [30]