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KPV, also known as Lysine-proline-valine, is a naturally occurring tripeptide [that] has been shown to attenuate the inflammatory responses of colonic cells[and] exerts its anti-inflammatory function inside cells, where it inactivates inflammatory pathways (Xiao et al., 2017)

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AUC is somewhat cumbersome to calculate in clinical context, and thus trough levels are frequently used as a surrogate