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SKU: 36563322849
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Preclinical studies in animal models have yielded several noteworthy findings

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Susceptibility variants such as p.E326K, p.T369M, p.N370S and p.L444P reduce glucocerebrosidase activity, impair lysosomal function and promote alpha-synuclein accumulation (Blauwendraat et al., 2020)