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For instance, a second dose of IVIg did not provide additional benefit over placebo and was associated with a higher frequency of serious adverse events in patients with severe GBS who deteriorated 1 week after their first course of IVIg (84)

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Many proteins which underwent dysregulated abundance under both basal and ROS conditions were reductases, oxidases, stress response proteins and enzymes with oxidising products (Supplementary Tables S3 and S4)