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Molecules 27(14):4663 Zingale E et al (2022) Drug nanocrystals: focus on brain delivery from therapeutic to diagnostic applications

doi: 10.3389/fendo.2023.1332114 Received 02 November 2023 Accepted 04 December 2023 Published 24 January 2024 Volume 14 - 2023 Edited by Stefano Zucchini, IRCCS University Hospital of Bologna Sant Orsola Polyclinic, Italy Reviewed by Cristina Partenope, Azienda Ospedaliero Universitaria Maggiore della Carit, Italy David Ingram, Childrens Mercy Kansas City, United States Updates Copyright 2024 Zaffanello, Pietrobelli, Cavarzere, Guzzo and Antoniazzi

In -cells, the rough endoplasmic reticulum ribosomes synthesize preproinsulin, which is cleaved into proinsulin and transported to the Golgi apparatus