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identified a novel cytokine profile associated with metastasis of NSCLC to TDLNs using EBUS TBNA ( 5.2 Cellular involvement in the nodal microenvironment The implications of varying cellular compositions of the TDLN microenvironment has been the subject of multiple studies in NSCLC (see Table 1 )

Adhering to these principles is fundamental for improving bioavailability, enhancing clinical potential, and ensuring the safe use of TCM

According to the fndings of many researchers, SeNPs are benefcial in the chemoprevention of cancer as a potential anticancer medication and carrier of anticancer drugs

This is a particular issue for drug metabolizing enzymes, especially cytochrome P450, which are substantially downregulated [139]