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Vazirani J, Basu S

However, the safety and efficacy of NPs have limited entrapment efficiency (with classical water emulsion polymerization procedures) which, consequently, requires the excessive administration of polymeric material

Nat Rev Endocrinol 2013;9:366-376

Poliovirus, with a 7.5 kb RNA genome, was the first virus fully reconstituted in an extract-based cell-free system, 854 with expression in HeLa cell extracts achieving titers up to 10 7 infectious particles/mL