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Neuropharmacology 54 , 11361142 (2008)

Off-Label Semaglutide Linked to Deaths, Hospitalizations

- with prolonged therapy: anatomical signs of pathology of the valvular apparatus of the heart (such as thickening of the valve leaflet , narrowing of the valve lumen, mixed pathology (narrowing and stenosis of the valve), confirmed by an echocardiographic study (EchoCG), conducted prior to the start of therapy