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10.1111/ped.13232 94

doi: 10.3389/fnagi.2021.700306 178

There always seems to be a shortage of candidates

This site-specific conjugation strategy, targeting the hinge cysteine residues, enables the generation of a highly homogeneous ADC population with a controlled DAR of 23, as characterized by hydrophobic interaction chromatography (HIC), minimizing the heterogeneity and aggregation risks common with stochastic conjugation methods [54]